Publications

Original Articles in Peer-Reviewed Journals

 
Title
Author(s)
Journal
Pub.
Year
Definition of epitopes and antigens recognized by vaccinia specific immune responses: their conservation in variola virus sequences, and use as a model system to study complex pathogens.

Sette A, Grey H, Oseroff C, Peters B, Moutaftsi M, Crotty S, Assarsson E, Greenbaum J, Kim Y, Kolla R, Tscharke D, Koelle D, Johnson RP, Blum J, Head S, Sidney J.  Vaccine.  2009
The smallpox vaccine induces an early neutralizing IgM response.

Moyron-Quiroz JE, McCausland MM, Kageyama R, Sette A, Crotty S.  Vaccine.  2009
Heavily isotype-dependent protective activities of human antibodies against vaccinia virus extracellular virion antigen B5.

Benhnia MR, McCausland MM, Laudenslager J, Granger SW, Rickert S, Koriazova L, Tahara T, Kubo RT, Kato S, Crotty S.  J Virol.  2009
Bcl6 and Blimp-1 are reciprocal and antagonistic regulators of T follicular helper cell differentiation.

Johnston RJ, Poholek AC, DiToro D, Yusuf I, Eto D, Barnett B, Dent AL, Craft J, Crotty S.  Science.  2009
Inhibition of NK cell activity by IL-17 allows vaccinia virus to induce severe skin lesions in a mouse model of eczema vaccinatum.

Kawakami Y, Tomimori Y, Yumoto K, Hasegawa S, Ando T, Tagaya Y, Crotty S, Kawakami T.  J Exp Med.  2009
Exploring immune memory. Interview by Kira Heller.  Crotty S.  J Exp Med.  2009
Vaccinia virus extracellular enveloped virion neutralization in vitro and protection in vivo depend on complement.

Benhnia MR, McCausland MM, Moyron J, Laudenslager J, Granger S, Rickert S, Koriazova L, Kubo R, Kato S, Crotty S.
J Virol.
2009
Bcl6 and Blimp-1 Are Reciprocal and Antagonistic Regulators of T Follicular Helper Cell Differentiation. (Supplementary Figure) Johnston RJ, Poholek AC, Ditoro D, Yusuf I, Eto D, Barnett B, Dent AL, Craft J, Crotty S. Science
2009
Quantitative PCR technique for detecting lymphocytic choriomeningitis virus in vivo. McCausland MM, Crotty S. J Virol Methods 2008
OX40 drives protective vaccinia virus-specific CD8 T cells.
Salek-Ardakani S, Moutaftsi M, Crotty S, Sette A, Croft M.
J Immunol.
2008
Selective CD4+ T cell help for antibody responses to a large viral pathogen: deterministic linkage of specificities.
Sette A, Moutaftsi M, Moyron-Quiroz J, McCausland MM, Davies DH, Johnston RJ, Peters B, Rafii-El-Idrissi Benhnia M, Hoffmann J, Su HP, Singh K, Garboczi DN, Head S, Grey H, Felgner PL, Crotty S.
Immunity
2008
NKT cells prevent chronic joint inflammation after infection with Borrelia burgdorferi.
Tupin E, Benhnia MR, Kinjo Y, Patsey R, Lena CJ, Haller MC, Caimano MJ, Imamura M, Wong CH, Crotty S, Radolf JD, Sellati TJ, Kronenberg M.
Proc Natl Acad Sci U S A.
2008
Redundancy and plasticity of neutralizing antibody responses are cornerstone attributes of the human immune response to the smallpox vaccine.

Benhnia MR, McCausland MM, Su HP, Singh K, Hoffmann J, Davies DH, Felgner PL, Head S, Sette A, Garboczi DN, Crotty S.
J Virol.
2008
SAP Regulation of Follicular Helper CD4 T Cell Development and Humoral Immunity Is Independent of SLAM and Fyn Kinase1.

McCausland MM, Yusuf I, Tran H, Ono N, Yanagi Y, Crotty S.
J Immunol.
2007
Vaccinia Virus H3L Envelope Protein Is a Major Target of Neutralizing Antibodies in Humans and Elicits Protection against Lethal Challenge in Mice.

Davies DH, McCausland MM, Valdez C, Huynh D, Hernandez JE, Mu Y, Hirst S, Villarreal L, Felgner PL, Crotty S.
J Virol.
2005
Profiling the humoral immune response to infection by using proteome microarrays: high-throughput vaccine and diagnostic antigen discovery.

Davies DH, Liang X, Hernandez JE, Randall A, Hirst S, Mu Y, Romero KM, Nguyen TT, Kalantari-Dehaghi M, Crotty S, Baldi P, Villarreal LP, Felgner PL.
Proc Natl Acad Sci U S A.
2005
Tracking human antigen-specific memory B cells: a sensitive and generalized ELISPOT system.

Crotty S, Aubert RD, Glidewell J, Ahmed R.
J Immunol Methods. 
2004
Immune responses to Bacillus anthracis protective antigen in patients with bioterrorism-related cutaneous or inhalation anthrax.
Quinn CP, Dull PM, Semenova V, Li H, Crotty S, Taylor TH, Steward-Clark E, Stamey KL, Schmidt DS, Stinson KW, Freeman AE, Elie CM, Martin SK, Greene C, Aubert RD, Glidewell J, Perkins BA, Ahmed R, Stephens DS.
J Infect Dis.
2004
Immunological memory in humans.
 
Crotty S, Ahmed R.
Semin Immunol. 
2004
Cutting edge: long-term B cell memory in humans after smallpox vaccination.
 
Crotty S, Felgner P, Davies H, Glidewell J, Villarreal L, Ahmed R.
J Immunol. 
2003
SAP is required for generating long-term humoral immunity. 

Crotty S, Kersh EN, Cannons J, Schwartzberg PL, Ahmed R.
Nature
2003
Ribavirin's antiviral mechanism of action: lethal mutagenesis?

Crotty S, Cameron C, Andino R.
J Mol Med.
2002
Protection against simian immunodeficiency virus vaginal challenge by using Sabin poliovirus vectors.
Crotty S, Miller CJ, Lohman BL, Neagu MR, Compton L, Lu D, Lü FX, Fritts L, Lifson JD, Andino R.
J Virol.
 2002
RNA virus error catastrophe: direct molecular test by using ribavirin.
Crotty S, Cameron CE, Andino R.
Proc Natl Acad Sci U S A.
 2001
The broad-spectrum antiviral ribonucleoside ribavirin is an RNA virus mutagen.

Crotty S, Maag D, Arnold JJ, Zhong W, Lau JY, Hong Z, Andino R, Cameron CE. Nat Med.
 2000
Cytotoxic T-cell immunity to virus-infected non-haematopoietic cells requires presentation of exogenous antigen.
 Sigal LJ, Crotty S, Andino R, Rock KL. Nature
 1999