Publications

Original Articles in Peer-Reviewed Journals

Title
Author(s)
Journal
Pub.
Year
Lyn- and PLC-{beta}3-dependent regulation of SHP-1 phosphorylation controls Stat5 activity and myelomonocytic leukemia-like disease.

Xiao W, Ando T, Wang HY, Kawakami Y, Kawakami T.  Blood.  2010
JNK1 controls mast cell degranulation and IL-1{beta}production in inflammatory arthritis.
 
Guma M, Kashiwakura J, Crain B, Kawkami Y, Beutler B, Firestein GS, Kawakami T, Karin M, Corr M.  P Natl Acad Sci USA.  2010
Tyrosine phosphorylation of SHIP promotes its proteasomal degradation.


Ruschmann J, Ho V, Antignano F, Kuroda E, Lam V, Ibaraki M, Snyder K, Kim C, Flavell RA, Kawakami T, Sly
L, Turhan AG, Krystal G. 
Exp Hematol.  2010
FcepsilonRI beta-chain ITAM amplifies P13K-signaling to ensure synergistic degranulation response via FcepsilonRI and adenosine receptors.

Nunomura S, Gon Y, Yoshimaru T, Kashiwakura J, Kawakami T, Ra C.
Eur J Immunol.  2010
A minor catalytic activity of Src family kinases is sufficient for maximal activation of mast cells via the highaffinity IgE receptor.

Poderycki M, Tomimori Y, Ando T, Xiao W, Maeda-Yamamoto M, Sauer K, Kawakami Y, Kawakami T.
J Immunol.  2010
Mast cells in atopic dermatitis.

Kawakami T, Ando T, Kimura M, Wilson BS, Kawakami Y.  Curr Opin Immunol.  2009
A crucial door to the mast cell mystery knocked in.
 
Kawakami T.  J Immunol.  2009
Small, mobile FcepsilonRI receptor aggregates are signaling competent.

Andrews NL, Pfeiffer JR, Martinez AM, Haaland DM, Davis RW, Kawakami T, Oliver JM, Wilson BS, Lidke DS.  Immunity.  2009
Polyclonal IgE induces mast cell survival and cytokine production.
 

Kashiwakura J, Kawakami Y, Yuki K, Zajonc DM, Hasegawa S, Tomimori Y, Caplan B, Saito H, Furue M, Oettgen HC, Okayama Y, Kawakami T.  Allergol Int.  2009
Tumor suppression by phospholipase C-beta3 via SHP-1-mediated dephosphorylation of Stat5.

 
Xiao W, Hong H, Kawakami Y, Kato Y, Wu D, Yasudo H, Kimura A, Kubagawa H, Bertoli LF, Davis RS, Chau LA, Madrenas J, Hsia CC, Xenocostas A, Kipps TJ, Hennighausen L, Iwama A, Nakauchi H, Kawakami T.  Cancer Cell.  2009
Inhibition of NK cell activity by IL-17 allows vaccinia virus to induce severe skin lesions in a mouse model of eczema vaccinatum.

Kawakami Y, Tomimori Y, Yumoto K, Hasegawa S, Ando T, Tagaya Y, Crotty S, Kawakami T.  J Exp Med.  2009
Pivotal advance: IgE accelerates in vitro development of mast cells and modifies their phenotype.

Kashiwakura J, Xiao W, Kitaura J, Kawakami Y, Maeda-Yamamoto M, Pfeiffer JR, Wilson BS, Blank U, Kawakami T. J Leukoc Biol. 2008
Regulation of myeloproliferation and M2 macrophage programming in mice by Lyn/Hck, SHIP, and Stat5.

Xiao W, Hong H, Kawakami Y, Lowell CA, Kawakami T. J Clin Invest. 2008
Human IgE+ and IgE- are not equivalent to mouse highly cytokinergic IgE.

Xie L, Schroeder JT, Langdon JM, Sora-Scott RS, Kawakami T, MacDonald SM.
J Allergy Clin Immunol.
2008
Basophils now enhance memory.
Kawakami T.
Nat Immunol.
2008