Publications

Original Articles in Peer-Reviewed Journals

Title
Author(s)
Journal
Pub.
Year
Enhanced infection of liver sinusoidal endothelial cells in a mouse model of antibody-induced severe dengue disease.
 
Zellweger RM, Prestwood TR, Shresta S.  Cell Host Microbe.  2010 
Cardif-mediated signaling controls the initial innate response to dengue virus in vivo.

Perry ST, Prestwood TR, Lada SM, Benedict CA, Shresta S.
J Virol.
2009
A protective role for dengue virus-specific CD8+ T cells.
Yauch LE, Zellweger RM, Kotturi MF, Qutubuddin A, Sidney J, Peters B, Prestwood TR, Sette A, Shresta S.
J Immunol.
2009
Mouse models of dengue virus infection and disease.

Yauch LE, Shresta S. Antiviral Res. 2008
A mouse-passaged dengue virus strain with reduced affinity for heparan sulfate causes severe disease in mice by establishing increased systemic viral loads.

Prestwood TR, Prigozhin DM, Sharar KL, Zellweger RM, Shresta S. J Virol. 2008
A murine model for dengue virus-induced lethal disease with increased vascular permeability. 

Shresta S, Sharar KL, Prigozhin DM, Beatty PR, Harris E.
J Virol.
2006
Critical roles for both STAT1-dependent and STAT1-independent pathways in the control of primary dengue virus infection in mice.

Shresta S, Sharar KL, Prigozhin DM, Snider HM, Beatty PR, Harris E.
J Immunol.
2005
Interferon-dependent Immunity is essential for resistance to primary dengue virus infection in mice, whereas T and B cell-dependent immunity are less critical.

Shresta S, Kyle JL, Snider HM, Basavapatna M, Beatty PR, Harris E.
J Virol.
2004
Early activation of natural killer and B cells in response to dengue virus infection in A/J mice.

Shresta S, Kyle JL, Robert Beatty P, Harris E.
Virology.
2004
ICOS co-stimulatory receptor is essential for T-cell activation and function.

Dong C, Juedes AE, Temann UA, Shresta S, Allison JP, Ruddle NH, Flavell RA.
Nature.
2001
Granzyme A initiates an alternative pathway for granule-mediated apoptosis.

Shresta S, Graubert TA, Thomas DA, Raptis SZ, Ley TJ.
Immunity.
1999
How do cytotoxic lymphocytes kill their targets?

Shresta S, Pham CT, Thomas DA, Graubert TA, Ley TJ.
Curr Opin Immunol.
1998
Residual cytotoxicity and granzyme K expression in granzyme A-deficient cytotoxic lymphocytes.

Shresta S, Goda P, Wesselschmidt R, Ley TJ.
J Biol Chem.
1997
Mechanisms responsible for granzyme B-independent cytotoxicity.

Shresta S, Russell JH, Ley TJ.
Blood.
1997
Profiles of pulp infiltrating lymphocytes at various times throughout feather regeneration in smyth line chickens with vitiligo.

Shresta S, Smyth JR Jr, Erf GF.
Autoimmunity.
1997
Natural killer and lymphokine-activated killer cells require granzyme B for the rapid induction of apoptosis in susceptible target cells.

Shresta S, MacIvor DM, Heusel JW, Russell JH, Ley TJ.
Proc Natl Acad Sci U S A.
1995
Granzyme B plays a critical role in cytotoxic lymphocyte induced apoptosis.

Shresta S, Heusel JW, Macivor DM, Wesselschmidt RL, Russell JH, Ley TJ.
Immunol Rev.
1995
Cytotoxic lymphocytes require granzyzme B for the rapid induction of DNA fragmentation and apoptosis in allogeneic target cells.
Heusel JW, Wesselschmidt RL, Shresta S, Russell JH, Ley TJ.
Cell.
1994