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Original Articles in Peer-Reviewed Journals
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Author(s)
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Pub.
Year
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How viral infections enhance or prevent type 1 diabetes-from mouse to man.
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von Herrath M, Filippi C, Coppieters K. |
J Med Virol. |
2011
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Development of Autoimmune Diabetes in the Absence of Detectable IL-17A in a CD8-Driven Virally Induced Model.
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Van Belle TL, Esplugues E, Liao J, Juntti T,
Flavell RA, von Herrath MG. |
J Immunol. |
2011
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How does type 1 diabetes develop?: the notion of homicide or β-cell suicide revisited.
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Atkinson MA, Bluestone JA, Eisenbarth GS, Hebrok M, Herold KC, Accili D, Pietropaolo M, Arvan PR, Von Herrath M, Markel DS, Rhodes CJ. |
Diabetes. |
2011
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Nasal cardiac myosin peptide treatment and OX40 blockade protect mice from acute and chronic virally-induced myocarditis.
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Fousteri G, Dave A, Morin B, Omid S, Croft M, von Herrath MG. |
J Autoimmun. |
2011
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TLR2 signaling improves immunoregulation to prevent type 1 diabetes.
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Filippi CM, Ehrhardt K, Estes EA, Larsson P, Oldham JE, von Herrath MG. |
Eur J Immunol. |
2011
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Viral infection prevents diabetes by inducing regulatory T cells through NKT cell-plasmacytoid dendritic cell interplay.
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Diana J, Brezar V, Beaudoin L, Dalod M, Mellor A, Tafuri A, von Herrath M, Boitard C, Mallone R, Lehuen A. |
J Exp Med. |
2011
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Type 1 diabetes: etiology, immunology, and therapeutic strategies.
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van Belle TL, Coppieters KT, von Herrath MG. |
Physiol Rev. |
2011
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Increased memory conversion of naïve CD8 T cells activated during late
phases of acute virus infection due to decreased cumulative antigen
exposure.
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Fousteri G, Dave A, Juedes A, Juntti T, Morin B, Togher L, Farber DL, von Herrath M. |
PLoS One. |
2011
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A novel technique for the in vivo imaging of autoimmune diabetes development in the pancreas by two-photon microscopy.
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Coppieters K, Martinic MM, Kiosses WB, Amirian N, von Herrath M. |
PLoS One.
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2010
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Humanizing animal models: a key to autoimmune diabetes treatment.
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Bresson D, von Herrath M. |
Sci Transl Med. |
2011
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Pathology and pathogenesis of virus infections.
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Baca Jones C, von Herrath M. |
The Immune Response to Infection
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2011 |
Antigen-specific immunotherapy for type 1 diabetes: maximizing the potential.
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Peakman M, von Herrath M. |
Diabetes.
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2010
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Combination therapies for type 1 diabetes: why not now?
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von Herrath M. |
Immunotherapy. |
2010
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Immunotherapy of type 1 diabetes--how to rationally prioritize combination therapies in T1D.
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Boettler T, von Herrath M. |
Int Immunopharmacol. |
2010 |
Subcutaneous insulin B:9-23/IFA immunisation induces Tregs that control
late-stage prediabetes in NOD mice through IL-10 and IFNgamma.
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Fousteri G, Dave A, Bot A, Juntti T, Omid S, von Herrath M. |
Diabetologia. |
2010 |
99th Dahlem conference on infection, inflammation and chronic
inflammatory disorders: viruses, autoimmunity and immunoregulation.
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Filippi CM, von Herrath MG. |
Clin Exp Immunol. |
2010 |
Minimal effect of CD103 expression on the control of a chronic antiviral immune response.
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Fousteri G, Dave A, Juntti T, Morin B, McClure M, von Herrath M. |
Viral Immunol. |
2010 |
Pre-existing autoimmunity determines type 1 diabetes outcome after Flt3-ligand treatment.
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Van Belle TL, Juntti T, Liao J, von Herrath MG. |
J Autoimmun. |
2010 |
Essential role for TLR9 in prime but not prime-boost plasmid DNA
vaccination to activate dendritic cells and protect from lethal viral
infection.
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Rottembourg D, Filippi CM, Bresson D, Ehrhardt K, Estes EA, Oldham JE, von Herrath MG. |
J Immunol. |
2010 |
Viral triggers for autoimmunity: is the 'glass of molecular mimicry' half full or half empty?
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Christen U, Hintermann E, Holdener M, von Herrath MG. |
J Autoimmun.
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2010 |
Genetic-induced variations in the GAD65 T-cell repertoire governs
efficacy of anti-CD3/GAD65 combination therapy in new-onset type 1
diabetes.
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Bresson D, Fradkin M, Manenkova Y, Rottembourg D, von Herrath M. |
Mol Ther. |
2010 |
Adenovirus E3 MHC inhibitory genes but not TNF/Fas apoptotic inhibitory genes expressed in beta cells prevent autoimmune diabetes.
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Horwitz MS, Efrat S, Christen U, von Herrath MG, Oldstone MB. |
Proc Natl Acad Sci USA. |
2009
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The role of the activating receptor NKG2D in autoimmunity.
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Van Belle TL, von Herrath MG. |
Mol Immunol. |
2009
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Immunotherapy for the prevention and treatment of type 1 diabetes: optimizing the path from bench to bedside.
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Bresson D, von Herrath M. |
Diabetes Care. |
2009
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Remodeling rodent models to mimic human type 1 diabetes.
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von Herrath M, Nepom GT. |
Eur J Immunol. |
2009
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Histopathology of type 1 diabetes: old paradigms and new insights.
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Coppieters KT, von Herrath MG. |
Rev Diabet Stud. |
2009
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Mouse models for type 1 diabetes.
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Van Belle TL, Taylor P, von Herrath MG. |
Drug Discov Today Dis Models. |
2009
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Immunoregulatory mechanisms triggered by viral infections protect from type 1 diabetes in mice.
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Filippi CM, Estes EA, Oldham JE, von Herrath MG. |
J Clin Invest. |
2009
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Diabetes: A virus-gene collaboration.
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von Herrath M. |
Nature. |
2009
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Interleukin-21 is required for the development of type 1 diabetes in NOD mice.
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Sutherland AP, Van Belle T, Wurster AL, Suto A, Michaud M, Zhang D, Grusby MJ, von Herrath M. |
Diabetes. |
2009
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NKT cell-plasmacytoid dendritic cell cooperation via OX40 controls viral infection in a tissue-specific manner.
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Diana J, Griseri T, Lagaye S, Beaudoin L, Autrusseau E, Gautron AS, Tomkiewicz C, Herbelin A, Barouki R, von Herrath M, Dalod M, Lehuen A. |
Immunity. |
2009
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CD103 is dispensable for anti-viral immunity and autoimmunity in a mouse model of virally-induced autoimmune diabetes.
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Fousteri G, Dave A, Juntti T, von Herrath M. |
J Autoimmun. |
2009
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No significant CTL cross-priming by dendritic cell-derived exosomes during murine lymphocytic choriomeningitis virus infection.
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Coppieters K, Barral AM, Juedes A, Wolfe T, Rodrigo E, Théry C, Amigorena S, von Herrath MG. |
J Immunol. |
2009
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How can we improve the translational landscape for a faster cure of type 1 diabetes?
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von Herrath M, Chan A. |
J Clin Invest. |
2009
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Animal models of human type 1 diabetes.
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von Herrath M, Nepom GT. |
Nat Immunol. |
2009
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Can we learn from viruses how to prevent type 1 diabetes?: the role of viral infections in the pathogenesis of type 1 diabetes and the development of novel combination therapies.
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von Herrath M. |
Diabetes. |
2009
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Resuscitating adaptive Tregs with combination therapies?
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Bresson D, von Herrath M.
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Novartis Found Symp. |
2008 |
Taking a closer look at the pancreas.
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Coppieters K, von Herrath M. |
Journal. |
2008 |
Transforming growth factor-beta suppresses the activation of CD8+
T-cells when naive but promotes their survival and function once
antigen experienced: a two-faced impact on autoimmunity.
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Filippi CM, Juedes AE, Oldham JE, Ling E, Togher L, Peng Y, Flavell RA, von Herrath MG.
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Diabetes.
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2008
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IL-10 and the resolution of infections.
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Filippi CM, von Herrath MG.
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J Pathol.
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2008
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Viral trigger for type 1 diabetes: pros and cons.
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Filippi CM, von Herrath MG.
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Diabetes.
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2008
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First-trimester human fetal pancreas transplantation for type 1
diabetes treatment: an alternative approach for achieving long-term
graft survival?
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Fousteri G, von Herrath M.
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Diabetes.
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2008
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Naive precursor frequencies and MHC binding rather than the degree of epitope diversity shape CD8+ T cell immunodominance.
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Kotturi MF, Scott I, Wolfe T, Peters B, Sidney J, Cheroutre H, von Herrath MG, Buchmeier MJ, Grey H, Sette A. |
J Immunol.
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2008
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Novel strategies to eliminate persistent viral infections.
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Martinic MM, von Herrath MG.
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Trends Immunol.
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2008
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Real-time imaging of the pancreas during development of diabetes.
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Martinic MM, von Herrath MG.
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Immunol Rev.
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2008
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Islet antigen specific IL-10+ immune responses but not CD4+CD25+FoxP3+
cells at diagnosis predict glycemic control in type 1 diabetes.
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Sanda S, Roep BO, von Herrath M.
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Clin Immunol.
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2008
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Murine antithymocyte globulin therapy alters disease progression in NOD mice by a time-dependent induction of immunoregulation.
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Simon G, Parker M, Ramiya V, Wasserfall C, Huang Y, Bresson D, Schwartz RF, Campbell-Thompson M, Tenace L, Brusko T, Xue S, Scaria A, Lukason M, Eisenbeis S, Williams J, Clare-Salzler M, Schatz D, Kaplan B, Von Herrath M, Womer K, Atkinson MA.
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Diabetes.
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2008
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Immunosuppression in islet transplantation.
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Van Belle T, von Herrath M.
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J Clin Invest.
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2008
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Defining optimal immunotherapies for type 1 diabetes. Introduction.
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von Herrath M.
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Novartis Found Symp.
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2008
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Towards a curative therapy in type 1 diabetes: remission of autoimmunity, maintenance and augmentation of beta cell mass.
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Waldron-Lynch F, von Herrath M, Herold KC.
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Novartis Found Symp.
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2008
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Exacerbated pathology of viral encephalitis in mice with central nervous system-specific autoantibodies.
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Burrer R, Buchmeier MJ, Wolfe T, Ting JP, Feuer R, Iglesias A, von Herrath MG.
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Am J Pathol.
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2007
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Minimal Impact of a De Novo-Expressed β-Cell Autoantigen on Spontaneous Diabetes Development in NOD Mice.
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Martinic MM, Juedes AE, Bresson D, Homann D, Skak K, Huber C, Ling E, Ejrnaes M, Wolfe T, Togher L, Christen U, von Herrath MG.
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Diabetes.
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2007
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SOCS-1 protects from virally-induced CD8 T cell mediated type 1 diabetes.
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Barral AM, Thomas HE, Ling EM, Darwiche R, Rodrigo E, Christen U, Ejrnaes M, Wolfe T, Kay TW, von Herrath MG. |
J Autoimmun. |
2006 |
Anti-CD3 and nasal proinsulin combination therapy enhances remission from recent-onset autoimmune diabetes by inducing Tregs.
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Bresson D, Togher L, Rodrigo E, Chen Y, Bluestone JA, Herold KC, von Herrath M.
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J Clin Invest.
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2006
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Resolution of a chronic viral infection after interleukin-10 receptor blockade.
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Ejrnaes M, Filippi CM, Martinic MM, Ling EM, Togher LM, Crotty S, von Herrath MG.
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J Exp Med.
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2006
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Tolerance tag team.
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von Herrath M, Homann D.
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Nat Med.
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2004
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CD8αα-mediated survival and differentiation of CD8 memory T cell precursors.
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Madakamutil LT, Christen U, Lena CJ, Wang-Zhu Y, Attinger A, Sundarrajan M, Ellmeier W, von Herrath MG, Jensen P, Littman DR, Cheroutre H.
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Science.
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2004
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T-bet controls autoaggressive CD8 lymphocyte responses in type 1 diabetes.
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Juedes AE, Rodrigo E, Togher L, Glimcher LH, von Herrath MG.
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J Exp Med.
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2004
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Induction, acceleration or prevention of autoimmunity by molecular mimicry.
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Christen U, von Herrath MG.
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Mol Immunol.
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2004
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Cure of prediabetic mice by viral infections involves lymphocyte recruitment along an IP-10 gradient.
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Christen U, Benke D, Wolfe T, Rodrigo E, Rhode A, Hughes AC, Oldstone MB, von Herrath MG.
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J Clin Invest.
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2004
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Introducing baselines for therapeutic use of regulatory T cells and cytokines in autoimmunity.
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von Herrath M, Homann D.
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Trends Immunol. |
2003
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